Bionacre® is developed from nacre. Ostenova brings together a porcine-derived bone substitute and collagen membranes. Each product follows its own pathway.
Nacre-derived range
Bionacre® Bone Graft.
Our nacre-derived bone substitute programme, developed for filling bone defects in dental surgery.
Nacre is a sophisticated mineral-organic architecture produced by a living organism. MEGA BIOPHARMA transforms this natural material into advanced biomaterials designed for regenerative medicine. Bone is our lead programme, with further research into cartilage and orthopaedic components.
BiomineralisationA living organism assembles a mineral phase and an organic matrix, layer by layer.
→
EngineeringProprietary processes to prepare, characterise and shape nacre.
→
The applicationsTissue-specific formats: granules, powders, compact forms and formulations under investigation.
Materials characterisation, cell biology, histology and preclinical assessment: a progressive approach to understanding how nacre interacts with tissues.
A scaffold studied for bone formation
New bone deposited around the particles
Biodegradation observed at eight weeks
Exploratory nacre powder study: two sheep, eight implanted sites and eight controls. A moderate local inflammatory response was also observed. These findings are not clinical validation of Bone Graft.
Hôtel-Dieu · Paris
