Understand nacre
Biomineralisation, architecture and biological interactions underpin our work.
Explore the scienceMEGA BIOPHARMA · Medical biomaterials
Bionacre®.
From nacre
to biomaterials.
We develop nacre-derived biomaterials for bone and tissue regeneration. Our first programme, Bionacre® Bone Graft, targets dental surgery.
Late preclinical stage · Preparing the regulatory pathway
5 patent familiesExpiry dates extending to 2040
ISO 9001Certified quality system · LNE
40+ publicationsWith our scientific collaborators
Why nacre?
A natural material.
A medical ambition.
Nacre combines a mineral structure with an organic matrix. Our research explores their interactions with living tissues to develop new approaches to bone repair.
Bionacre®
Proprietary processes to prepare, characterise and shape nacre.
Explore the platformBone Graft
Nacre-based granules being developed for filling dental bone defects.
Explore the programme
Our first programme
Bionacre®
Bone Graft.
Bone regeneration in dental surgery is our first application. The programme is in late preclinical development.
Next steps: complete the assessments and prepare regulatory submissions, with a planned US FDA 510(k) pathway.
Request the roadmapBionacre® Bone Graft has not received FDA clearance for marketing in the United States.
One team, one ambition
“Our ambition is to turn nacre’s potential into medical biomaterials. With Bionacre®, we bring together research, industrial expertise and regulatory development around a first programme: bone regeneration.”
Joël Drai · Founder & Chairman
Research & manufacturing in France
From our laboratories
to the next milestones.
In Crosne, our teams connect research, nacre processing and quality control. A network of experts supports our biomaterials development.