Orthopaedics
Bone grafts, remedying loss of bone substance, bone reconstruction and bone fusion are being performed increasingly frequently in orthopaedic and traumatic surgery (vertebral fusion, vertebroplasty, joint reconstruction, traumatology, etc.). As a result, there is an increasing need for bone fillers. The ageing population and obesity are found to be the main reasons;
Nacre, a biomaterial similar to bone
Since the early 90’s, the Doctors Camprasse have carried out a very large number of pre-clinical then pre-clinical experimentations on animal subjects and critical clinical cases. They have shown that nacre – a biomaterial consisting mainly of calcium – is particularly suited to bone repair, not least thanks to its osteomimetic properties.
MEGA BIOPHARMA is working on the development of implantable medical devices with mechanical properties appropriate for orthopaedic use:
- Bone substitutes (pouder form)
- Osteosynthesis materials (screws, rods, plates, other)
- Substitute bone pieces
Bionacre®, innovative technology for multiple orthopaedic applications
Bionacre® in powder form
Trauma
Product / Use: Substitutes for filling, reconstructing and repairing fractures (coagulum)
Key properties: osteogenic, haemostasis, biocompatible, bioabsorbable, radiopaque, no volume reduction.
Coagulum formed from Bionacre® in powder form and the patient’s blood
Spinal column
Product / Use: injectable bone substitute for vertebroplasty and kyphoplasty
Key properties: osteogenic, homeostatic, biocompatible, bioabsorbable, radiopaque, no volume reduction, no exothermic reaction.
Injectable cement made from Bionacre® in powder form
Joint reconstruction
Product / use: biological cements, watertight cements, for fixing the implant in place in the bone.
Key properties: osteogenic, homeostatic, biocompatible, bioabsorbable, radiopaque, no volume reduction, no exothermic reaction.
Biological cement made from Bionacre® in powder form
Bionacre® in solid form
Trauma
Product / use: plates, screws, rods, spacers, intramedullary nails.
Key properties: osteogenic, homeostatic, biocompatible, bioerodible, radiopaque, no volume reduction, no exothermic reaction.
Advantages:
- No second operation to remove implants: less stress for the patient, lower costs for the healthcare system.
- Superior ease of use for surgeons compared to existing technologies. Can take the place of autografts in repair and replacement procedures.
