Orthopaedics

Bone grafts, remedying loss of bone substance, bone reconstruction and bone fusion are being performed increasingly frequently in orthopaedic and traumatic surgery (vertebral fusion, vertebroplasty, joint reconstruction, traumatology, etc.). As a result, there is an increasing need for bone fillers. The ageing population and obesity are found to be the main reasons;

Mother-of-pearl, a biomaterial similar to bone

Since the early 90’s, the Doctors Camprasse have carried out a very large number of pre-clinical then pre-clinical experimentations on animal subjects and critical clinical cases. They have shown that mother-of-pearl – a biomaterial consisting mainly of calcium – is particularly suited to bone repair, not least thanks to its osteomimetic properties.

MEGA BIOPHARMA is working on the development of implantable medical devices with mechanical properties appropriate for orthopaedic use:

  • Bone substitutes (pouder form)
  • Osteosynthesis materials (screws, rods, plates, other)
  • Substitute bone pieces

Bionacre®, innovative technology for multiple orthopaedic applications

Bionacre® in powder form

Trauma

Product / Use: Substitutes for filling, reconstructing and repairing fractures (coagulum)

Key properties: osteogenic, haemostasis, biocompatible, bioabsorbable, radiopaque, no volume reduction.

Coagulum formed from Bionacre® in powder form and the patient’s blood

Spinal column

Product / Use: injectable bone substitute for vertebroplasty and kyphoplasty

Key properties: osteogenic, homeostatic, biocompatible, bioabsorbable, radiopaque, no volume reduction, no exothermic reaction.

Injectable cement made from Bionacre® in powder form

Joint reconstruction

Product / use: biological cements, watertight cements, for fixing the implant in place in the bone.

Key properties: osteogenic, homeostatic, biocompatible, bioabsorbable, radiopaque, no volume reduction, no exothermic reaction.

Biological cement made from Bionacre® in powder form

Bionacre® in solid form

Trauma

Product / use: plates, screws, rods, spacers, intramedullary nails.

Key properties: osteogenic, homeostatic, biocompatible, bioerodible, radiopaque, no volume reduction, no exothermic reaction.

Advantages:

  • No second operation to remove implants: less stress for the patient, lower costs for the healthcare system.
  • Superior ease of use for surgeons compared to existing technologies. Can take the place of autografts in repair and replacement procedures.