Orthopaedics
Bone grafts, remedying loss of bone substance, bone repair and reconstruction are being performed increasingly frequently in orthopaedic surgery (vertebral fusion, vertebroplasty, joint reconstruction, traumatology, etc.). As a result, there is an increasing need for bone fillers and bone substitutes. The ageing population and obesity are found to be the main reasons.
Mother-of-pearl, a biomaterial similar to bone
Since the early 90’s, the Doctors Camprasse have carried out a very large number of clinical and pre-clinical experimentations on animal subjects. They have shown that mother-of-pearl – a biomaterial consisting mainly of calcium – is particularly suited to bone repair, not least thanks to its osteomimetic properties.
MEGA BIOPHARMA is working on the development of implantable medical devices with mechanical properties appropriate for orthopaedic use:
- Bone substitutes (in the form of injectables or coagulum)
- Osteosynthesis elements (screws, rods, plates, other)
- Substitute bone pieces (intervertebral spacers)
Bionacre®, innovative technology for multiple orthopaedic applications
Bionacre® in powder form
Trauma
Product / Use: bone graft substitutes for filling, reconstructing and repairing fractures (coagulum)
Properties: osteogenic, haemostasis’ being dependent on calcium, good acceptance by the surrounding tissue.
Coagulum made from Bionacre® in powder form and the patient’s blood
Spinal column
Product / use: injectable cements for vertebroplasty and kynoplasty
Properties: non dose-dependent, natural radio opacity, no reduction in volume, no exothermic reaction, rapid healing process.
Injectable cement made from Bionacre® in powder form
Joint reconstruction
Product / use: biological cements, watertight cements, for fixing the implant in place in the bone.
Properties: no exothermic reaction, rapid healing process, stimulation of angiogenesis.
Biological cement made from Bionacre® in powder form
Bionacre® in solid form
Trauma
Product / use: plates, screws, rods, spacers, intramedullary nails – orthopaedic devices of the autograft type, suited to fractures
Properties: tight bonding, micro-movement and angiogenesis.
Advantages:
- No second operation to remove implants: less stress for the patient, lower costs for the healthcare system.
- Superior ease of use for surgeons compared to existing technologies. Can take the place of autografts in repair and replacement procedures.
Spinal column
Product / use: intersomatic cages, artificial discs, core replacement; treatment of spinal column diseases and vertebral fractures.
Properties: biological fixation (fusion procedures), no generation of harmful débris, natural radio opacity.
Joint reconstruction
Product / use: mono-compartment and multi-compartment devices for repairing faulty joints, compartmental implants suitable for the shoulder, knee, upper and lower limbs.
Properties: good acceptance by the surrounding tissue, no generation of harmful débris.
