Bone grafts, remedying loss of bone substance, bone repair and reconstruction are being performed increasingly frequently in orthopaedic surgery (vertebral fusion, vertebroplasty, joint reconstruction, traumatology, etc.). As a result, there is an increasing need for bone fillers and bone substitutes. The ageing population and obesity are found to be the main reasons.
Since the early 90’s, the Doctors Camprasse have carried out a very large number of clinical and pre-clinical experimentations on animal subjects. They have shown that mother-of-pearl – a biomaterial consisting mainly of calcium – is particularly suited to bone repair, not least thanks to its osteomimetic properties.
MEGA BIOPHARMA is working on the development of implantable medical devices with mechanical properties appropriate for orthopaedic use:
- Bone substitutes (in the form of injectables or coagulum)
- Osteosynthesis elements (screws, rods, plates, other)
- Substitute bone pieces (intervertebral spacers)
Product / Use: bone graft substitutes for filling, reconstructing and repairing fractures (coagulum)
Properties: osteogenic, haemostasis’ being dependent on calcium, good acceptance by the surrounding tissue.
Coagulum made from Bionacre® in powder form and the patient’s blood
Product / use: injectable cements for vertebroplasty and kynoplasty
Properties: non dose-dependent, natural radio opacity, no reduction in volume, no exothermic reaction, rapid healing process.
Injectable cement made from Bionacre® in powder form
Product / use: biological cements, watertight cements, for fixing the implant in place in the bone.
Properties: no exothermic reaction, rapid healing process, stimulation of angiogenesis.
Product / use: plates, screws, rods, spacers, intramedullary nails – orthopaedic devices of the autograft type, suited to fractures
Properties: tight bonding, micro-movement and angiogenesis.
- No second operation to remove implants: less stress for the patient, lower costs for the healthcare system.
- Superior ease of use for surgeons compared to existing technologies. Can take the place of autografts in repair and replacement procedures.
Product / use: intersomatic cages, artificial discs, core replacement; treatment of spinal column diseases and vertebral fractures.
Properties: biological fixation (fusion procedures), no generation of harmful débris, natural radio opacity.
Product / use: mono-compartment and multi-compartment devices for repairing faulty joints, compartmental implants suitable for the shoulder, knee, upper and lower limbs.
Properties: good acceptance by the surrounding tissue, no generation of harmful débris.